Candida species (spp.) are a normal part of the gut microbiome in 40-80% of the population. When in balance, they provide benefits to the host, such as protecting against pathogens. When overgrown, Candida spp. wreak havoc on the digestive system and can directly contribute to chronic illness.

This in depth webinar provides integrative and functional health practitioners with a comprehensive overview of gastrointestinal (GI) Candida spp. overgrowth and holistic treatment approaches that you can start using in your practice today.

https://www.youtube.com/watch?v=kr8J9qt6Z_Y

Dr. Blake Myers, a naturopathic doctor with over a decade of clinical experience, teaches you the key biological underpinnings of Candida spp. as a genus of organisms, how to recognize potential GI overgrowth in your patients, and currently available testing options.

After this foundational background, Dr. Myers takes you step by step through a naturopathic and functional medicine protocol, developed from over a decade of practice experience.

As you will see in this webinar, treatment of GI Candida overgrowth goes far beyond killing the organisms themselves. Dr. Blake emphasizes throughout this educational presentation that as practitioners we have one goal – to restore health in our patients and clients. Accomplishing this requires thinking differently than the simple anti-microbial methods of conventional medicine – especially in chronic cases. Dr. Blake will guide in approaching health and healing from this perspective.

Who is this webinar designed for?

Practitioners of any experience level, whether conventionally or functionally trained, who want to understand effective methods to restore health in patients with chronic dysbiosis and Candida gut overgrowth.

Non-practitioners will also find a great deal of information in this presentation that they can use to naturally support healthy digestive function and maintain gut health.

Link to actual slides: https://blog.canxida.com/wp-content/uploads/2024/01/gi-overgrowth-of-candida-slides.pdf

Webinar References

Slide 4:
Hou K, Wu ZX, Chen XY, et al. Microbiota in health and diseases. Signal Transduct Target Ther. 2022;7(1):135. Published 2022 Apr 23. doi:10.1038/s41392-022-00974-4

Richard ML, Sokol H. The gut mycobiota: insights into analysis, environmental interactions and role in gastrointestinal diseases. Nat Rev Gastroenterol Hepatol. 2019;16(6):331-345. doi:10.1038/s41575-019-0121-2

Slide 5:
Aggarwal N, Kitano S, Puah GRY, Kittelmann S, Hwang IY, Chang MW. Microbiome and Human Health: Current Understanding, Engineering, and Enabling Technologies. Chem Rev. 2023;123(1):31-72. doi:10.1021/acs.chemrev.2c00431

Margolis KG, Cryan JF, Mayer EA. The Microbiota-Gut-Brain Axis: From Motility to Mood. Gastroenterology. 2021;160(5):1486-1501. doi:10.1053/j.gastro.2020.10.066

Ogunrinola GA, Oyewale JO, Oshamika OO, Olasehinde GI. The Human Microbiome and Its Impacts on Health. Int J Microbiol. 2020;2020:8045646. Published 2020 Jun 12. doi:10.1155/2020/8045646

Slide 6:
Kumamoto CA, Gresnigt MS, Hube B. The gut, the bad and the harmless: Candida albicans as a commensal and opportunistic pathogen in the intestine. Curr Opin Microbiol. 2020;56:7-15. doi:10.1016/j.mib.2020.05.006

Romo JA, Kumamoto CA. On Commensalism of Candida. J Fungi (Basel). 2020;6(1):16. Published 2020 Jan 17. doi:10.3390/jof6010016

Slide 9:
Romo JA, Kumamoto CA. On Commensalism of Candida. J Fungi (Basel). 2020;6(1):16. Published 2020 Jan 17. doi:10.3390/jof6010016

Slide 10:
Li H, Miao MX, Jia CL, et al. Interactions between Candida albicans and the resident microbiota. Front Microbiol. 2022;13:930495. Published 2022 Sep 20. doi:10.3389/fmicb.2022.930495

Slide 11:
Romo JA, Kumamoto CA. On Commensalism of Candida. J Fungi (Basel). 2020;6(1):16. Published 2020 Jan 17. doi:10.3390/jof6010016
Williams RB, Lorenz MC. Multiple Alternative Carbon Pathways Combine To Promote Candida albicans Stress Resistance, Immune Interactions, and Virulence. mBio. 2020;11(1):e03070-19. Published 2020 Jan 14. doi:10.1128/mBio.03070-19

Slide 13:
Aminzadeh A, Sabeti Sanat A, Nik Akhtar S. Frequency of Candidiasis and Colonization of Candida albicans in Relation to Oral Contraceptive Pills. Iran Red Crescent Med J. 2016;18(10):e38909. Published 2016 Aug 17. doi:10.5812/ircmj.38909

Cheng G, Yeater KM, Hoyer LL. Cellular and molecular biology of Candida albicans estrogen response. Eukaryot Cell. 2006;5(1):180-191. doi:10.1128/EC.5.1.180-191.2006

Drummond RA, Desai JV, Ricotta EE, et al. Long-term antibiotic exposure promotes mortality after systemic fungal infection by driving lymphocyte dysfunction and systemic escape of commensal bacteria. Cell Host Microbe. 2022;30(7):1020-1033.e6. doi:10.1016/j.chom.2022.04.013

Gombart AF, Pierre A, Maggini S. A Review of Micronutrients and the Immune System-Working in Harmony to Reduce the Risk of Infection. Nutrients. 2020;12(1):236. Published 2020 Jan 16. doi:10.3390/nu12010236

Grotto D, Zied E. The Standard American Diet and its relationship to the health status of Americans. Nutr Clin Pract. 2010;25(6):603-612. doi:10.1177/0884533610386234

Jenkins WM, Macfarlane TW, Ferguson MM, Mason DK. Nutritional deficiency in oral candidosis. Int J Oral Surg. 1977;6(4):204-210. doi:10.1016/s0300-9785(77)80010-0

Kumwenda P, Cottier F, Hendry AC, et al. Estrogen promotes innate immune evasion of Candida albicans through inactivation of the alternative complement system. Cell Rep. 2022;38(1):110183. doi:10.1016/j.celrep.2021.110183

Man A, Ciurea CN, Pasaroiu D, et al. New perspectives on the nutritional factors influencing growth rate of Candida albicans in diabetics. An in vitro study. Mem Inst Oswaldo Cruz. 2017;112(9):587-592. doi:10.1590/0074-02760170098

Reider CA, Chung RY, Devarshi PP, Grant RW, Hazels Mitmesser S. Inadequacy of Immune Health Nutrients: Intakes in US Adults, the 2005-2016 NHANES. Nutrients. 2020;12(6):1735. Published 2020 Jun 10. doi:10.3390/nu12061735

Segerstrom SC, Miller GE. Psychological stress and the human immune system: a meta-analytic study of 30 years of inquiry. Psychol Bull. 2004;130(4):601-630. doi:10.1037/0033-2909.130.4.601

Spinillo A, Capuzzo E, Acciano S, De Santolo A, Zara F. Effect of antibiotic use on the prevalence of symptomatic vulvovaginal candidiasis. Am J Obstet Gynecol. 1999;180(1 Pt 1):14-17. doi:10.1016/s0002-9378(99)70141-9

Wilton L, Kollarova M, Heeley E, Shakir S. Relative risk of vaginal candidiasis after use of antibiotics compared with antidepressants in women: postmarketing surveillance data in England. Drug Saf. 2003;26(8):589-597. doi:10.2165/00002018-200326080-00005

Slide 25-29 and 31-35:
Remove Whitepaper: https://candida.yeastinfection.org/wp-content/uploads/2022/customer-files/canxida_remove_whitepaper.pdf
Restore Whitepaper: https://candida.yeastinfection.org/wp-content/uploads/2022/customer-files/canxida_restore_whitepaper.pdf
Rebuild Whitepaper: https://candida.yeastinfection.org/wp-content/uploads/2022/customer-files/canxida_rebuild_whitepaper.pdf

Slide 30:
Jadhav SB, Shah N, Rathi A, Rathi V, Rathi A. Serratiopeptidase: Insights into the therapeutic applications. Biotechnol Rep (Amst). 2020;28:e00544. Published 2020 Oct 17. doi:10.1016/j.btre.2020.e00544

Slide 45-47:
CanXida ReCharge Whitepaper: https://blog.canxida.com/wp-content/uploads/2024/01/recharge_whitepaper.pdf

Slide 55:
McKeown NM, Fahey GC Jr, Slavin J, van der Kamp JW. Fibre intake for optimal health: how can healthcare professionals support people to reach dietary recommendations?. BMJ. 2022;378:e054370. Published 2022 Jul 20. doi:10.1136/bmj-2020-054370

3-Phase Candida Clinical Protocol: https://blog.canxida.com/wp-content/uploads/2024/02/canxida-3-phase-candida-clinical-protocol.pdf

Corrections to the Webinar Content

Slide 13: Corticosteroids may increase risk for candida overgrowth due to immune suppressive effects.

Erdoğan T, Karakaya G, Kalyoncu AF. The Frequency and Risk Factors for Oropharyngeal Candidiasis in Adult Asthma Patients Using Inhaled Corticosteroids. Turk Thorac J. 2019;20(2):136-139. Published 2019 Jan 31. doi:10.5152/TurkThoracJ.2019.17011916

CanXida Formula Remove and Rebuild are tablets and I mistakenly said capsule. CanXida Formula Restore is a capsule.

Slide 56: I said AcH receptors on intraepithelial lymphocytes and it is Aryl hydrocarbon receptors (AhR) that brassica stimulate to help maintain these immune cells.

Gutiérrez-Vázquez C, Quintana FJ. Regulation of the Immune Response by the Aryl Hydrocarbon Receptor. Immunity. 2018;48(1):19-33. doi:10.1016/j.immuni.2017.12.012

Li Y, Innocentin S, Withers DR, et al. Exogenous stimuli maintain intraepithelial lymphocytes via aryl hydrocarbon receptor activation. Cell. 2011;147(3):629-640. doi:10.1016/j.cell.2011.09.025